Antibacterial Activity of Chloramphenicol-Related Compounds toward a Chloramphenicol-Resistant Strains ofStaphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus.
Chloramphenicol-resistant strains of Staphylococcus aureus contain an inducible enzyme which inactivates chloramphenicol by acetylation in the presence of acetyl coenzyme A. The products of acetylation are chromatographically indistinguishable from those obtained with chloramphenicol-resistant Escherichia coli harboring an R factor. The kinetics of induction of chloramphenicol acetyltransferase...
متن کاملChloramphenicol-resistant strains of Salmonella typhosa.
Changes that occur in gram-positive organisms coincident to the acquisition of resistance to such antibiotics as penicillin, streptomycin, and aureomycin are well documented (Gezon, 1948; Gezon and Cryst, 1948; Gezon and Fasan, 1950; Ramsey and Padron, 1954). However, with the exception of studies with Escherichia coli (Coffey et al., 1950; Bergersen, 1953) the changes in such gram-negative ent...
متن کاملKinetics of induction and purification of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus.
Plasmid-mediated chloramphenicol resistance in Staphylococcus aureus has been shown to involve acetylation of chloramphenicol by an enzyme induced by growth in the presence of the antibiotic and certain analogues. Analysis of the kinetics of induction has been complicated by (i) the intrinsic inhibitory effects of chloramphenicol on induced enzyme synthesis and (ii) the rapid disappearance of i...
متن کاملIn vitro susceptibility of chloramphenicol against methicillin-resistant Staphylococcus aureus.
OBJECTIVE To determine the in vitro susceptibility of chloramphenicol against methicillin-resistant Staphylococcus aureus. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Department of Microbiology, Armed Forces Institute of Pathology, Rawalpindi, from January to June 2012. METHODOLOGY One hundred and seventy four isolates of methicillin-resistant Staphylococcus aureus wer...
متن کاملNutritional requirements of two chloramphenicol resistant strains of Escherichia coli.
A series of investigation on the mechanism of chloramphenicol* resistance has been carried out in this laboratory, using CM resistant strains of E. coli, strains B and BO54. The present paper is concerned with the minimal nutritional requirement of these strains. Strains : E. coli B parent strain was given by Prof. Watanabe, Tokyo University, and BO54 parent strain by Prof. Akiba, Tokyo Univers...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Microbiology
سال: 1972
ISSN: 0021-5139
DOI: 10.1111/j.1348-0421.1972.tb00685.x